Jen from Jensense has a good Interview with Jason Calacanis about Weblogs Inc’s experience with Adsense. There’s lots covered but here’s Jason’s main piece of advice:
‘Jen: What is the best piece of advice you have for a publisher brand new to AdSense? What would you have done differently when you started with AdSense, knowing what you do now.
Jason: I would have run four ads per page, taken off the borders, and made the links the same color as the links on the blog. I would have also made channels for each position and blog so I could track things better.’